High Purity Chimeric P53 Penetrating Peptide Pnc-27

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: PNC-27
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Powder Raw: Yes
• Concealed Transportation: Yes
• Freight Timeliness: 10-15days
• Transportation: Camouflage
• Transport Package: Covert Disguise
• Specification: 1-10mg
• Trademark: uther
• Origin: China
• HS Code: 0101101010
• Production Capacity: 10000vials/Week

Product Description

Product Description

 

Product Details

Purity	99%+	Custom content	2mg 5mg 10mg 15mg 20mg 30me etc.
Actual peptide content	Exceed the standard	Payment method	Bank Transfer BTC USDT Paypal
Cleanliness	Sterile	Transportation time	7-15days
Test Report	COA  HPLC  Third party testing	Disguise	Can provide
Customized top color	Red Yellow Blue Black Purple White Green	Resend policy	According to different countries

PNC-27, an anticancer peptide, containing an HDM-2 binding domain corresponding to p53 residues 12-26 and a transmembrane penetrating domain, has been found to kill cancer cells but not normal cells by inducing membrane lysis. The 3D structure of the p53 residue of PNC-27 directly overlaps the structure of the same residue that binds HDM-2, suggesting that this peptide may target HDM-2 in the cell membrane. The researchers found significant levels of HDM-2 in the cell membranes of a variety of cancer cells but not in some untransformed cell lines. In colocalization experiments, PNC-27 bound to cell membrane-bound HDM-2. The researchers used a membrane localization signal to transfect a plasmid expressing full-length HDM-2 into PNC-27-insensitive untransformed MCF-10-2A cells and found that these cells expressed full-length HDM-2 on their cell surface. cells versus PNC-27. We concluded that PNC-27 targets HDM-2 in cancer cell membranes, allowing it to selectively induce membrane lysis in these cells.

Company Profile

Packaging & Shipping

Comments and testing reports

 

FAQ

Q1: About the after-sale service of products
A: After purchasing the products from our factory, we have A professional technical team and after-sales team to serve you and solve all your problems in the future

Q2: Can I get some samples?
A: Yes, we can provide samples, but the customer will pay the freight.

Q3: How do I start paying?
Payment can be made by Bitcoin,wire transfer or Western Union or paypal

Q4: How to confirm product quality before placing an order?
A: You can get free samples of some products. You just have to pay the shipping fee or arrange for the sample to be sent to us by express.
You can send us your product specifications and requirements and we will produce products according to your requirements.

Q5: What is your MOQ?
A: The minimum quantity we can order is 1kg.
But usually we can accept a smaller quantity, say 100g, at the cost of 100% sample charge.

Q6: Shipping Time?
A: We ship the parcel out in 3-7 days and offer tracking No.. Shipping time is different to different country. Please consult.
 
 

Welcome to be our distinguished customer, please do not hesitate to contact us!