Weight Loss Peptides Retatrutide CAS 2381089-83-2 Janoshik Test

• Purity: 99.99
• Powder Raw: Yes
• Concealed Transportation: Yes
• Freight Timeliness: 10-15days
• Transport Package: Covert Disguise
• Specification: 1mg-10mg
• Model NO.: LY-3437943
• Trademark: uther
• Origin: China
• HS Code: 0101101010
• Production Capacity: 10000vials/Week

Product Description

 

Product Description

Retarutide (RETA) is a glucose dependent insulin-like peptide (GIP), glucagon like peptide-1 (GLP-1), and glucagon (GCG) multi receptor agonist. Previous studies have shown that once weekly injection of Retatrutide can significantly improve blood glucose control and lipid metabolism in patients with type 2 diabetes (T2D), and also has a strong weight loss effect!

On June 26, the 83rd American diabetes Association (ADA) academic conference released the latest clinical trial data of Relatrutide in the treatment of obesity and nonalcoholic fatty liver disease (NAFLD). On the same day, the New England Journal of Medicine (NEJM) published online the results of the Phase 2 clinical trial of Rotarutide for the treatment of obesity.
    

This randomized, double-blind phase 2 clinical trial evaluated the weight loss effect and safety of placebo and different doses of Retarutide after 48 weeks of treatment.

In the study, adults with BMI ≥ 30 kg/m2 or BMI 27-30 kg/m2 and at least one weight related disease (except for diabetes) were randomly allocated and treated with Rotarutide injection at a ratio of 2:1:1:1:2:2. The doses were 1 mg, 4 mg (initial dose 2 mg), 4 mg (initial dose 4 mg), 8 mg (initial dose 2 mg), 8 mg (initial dose 4 mg), 12 mg (initial dose 2 mg), respectively.

The main endpoint of clinical trials is the percentage change in body weight from baseline to 24 weeks. Secondary endpoints include the percentage of weight change from baseline to 48 weeks, the proportion of weight loss ≥ 5%, ≥ 10%, ≥ 15%, and the safety of treatment.

The average age of the 338 patients enrolled was 48.2 years, with males accounting for 51.8%. There was no significant difference in baseline characteristics among different treatment groups.
Compared to placebo, all doses of Rotarutide treatment showed clinically significant weight loss and had a better weight loss effect on women.
The weekly injection of Rotarutide (12 mg) resulted in an average weight loss of 24.2% in patients after 48 weeks, which is the best drug weight loss effect achieved so far.

Injecting Rotarutide (12 mg) weekly, all patients can achieve weight loss>5%; Nearly half of the patients can achieve weight loss of ≥ 25%; 1/4 of patients can achieve weight loss of ≥ 30%.

When the weekly injection dose is 8 mg, all patients achieve a weight loss of>5% after 48 weeks regardless of the dose.
The safety of Rotarutide in the NAFLD subgroup is similar to that in the obese population, and no liver toxicity was found within 48 weeks of treatment

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FAQ

Q1: About the after-sale service of products
A: After purchasing the products from our factory, we have A professional technical team and after-sales team to serve you and solve all your problems in the future

Q2: Can I get some samples?
A: Yes, we can provide samples, but the customer will pay the freight.

Q3: How do I start paying?
Payment can be made by Bitcoin,wire transfer or Western Union or paypal

Q4: How to confirm product quality before placing an order?
A: You can get free samples of some products. You just have to pay the shipping fee or arrange for the sample to be sent to us by express.
You can send us your product specifications and requirements and we will produce products according to your requirements.

Q5: What is your MOQ?
A: The minimum quantity we can order is 1kg.
But usually we can accept a smaller quantity, say 100g, at the cost of 100% sample charge.

Q6: Shipping Time?
A: We ship the parcel out in 3-7 days and offer tracking No.. Shipping time is different to different country. Please consult.
 
 

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